Description:
Nanocs Maleimide PEG PFP (Pentafluorophenyl) is a heterobifunctional PEG derivative that can react with both thiol and amine groups. Maleimide reacts with sulfhydryl groups at pH 6.5-7.5 to form stable thiol-ether bond while PFP reacts with amine groups at pH 7-9 to form stable aminde bond. Compared to other amine reactive linkers, PFP has higher reactivity yet with better stability in aqueous buffer. PFP reacts not only with primary amine, but also with secondary amine groups.
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Nanocs Inc.是全球领先的PEG修饰剂(PEG derivatives, PEGylation试剂)供应商,拥有种类齐全的PEG衍生物,包括:NHS-PEG,马来酰亚胺PEG,巯基PEG,氨基PEG,叠氮PEG,DSPE PEG,荧光PEG等。为全世界数以百万计的客户提供产品与服务。修饰性PEG可应用于药物输送、医疗设备改造和诊断分析等领域。Nanocs提供从磷脂PEGs到荧光PEGs的多种选择,种类齐全,产品线丰富。