Description:
Nanocs SnapLink TMmaleimide PEG NHS is a pegylated, amine and sulfhydryl reactive cross-linker. This cross-linker is non-cleavable and water soluble. It contains an amine reactive, NHS ester and a sulfhydryl reactive maleimide group linked with polyethylene glycol of different length. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. NHS esters react with deprotonated primary amines in pH 7-9. The maleimide group reacts with thiol groups at pH 6.5~7.5 to form stable thioether bonds.
Physical Properties:
- Appearance: Off-white semi-solid or solid;
- Reactivity: Reactive to sulfhydryl and amine groups;
- Solubility: Soluble in DMSO or DMF.
Storage Conditions:
- Store at -20 0C, desiccated. Avoid frequent thaw and freeze.
Nanocs Inc.是全球领先的PEG修饰剂(PEG derivatives, PEGylation试剂)供应商，拥有种类齐全的PEG衍生物，包括：NHS-PEG，马来酰亚胺PEG，巯基PEG，氨基PEG，叠氮PEG，DSPE PEG，荧光PEG等。为全世界数以百万计的客户提供产品与服务。修饰性PEG可应用于药物输送、医疗设备改造和诊断分析等领域。Nanocs提供从磷脂PEGs到荧光PEGs的多种选择，种类齐全，产品线丰富。
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