Synonym: Aminooxy PEG Lipoic acid, Oxyamine PEG Lipoic acid, Hydroxyamine PEG Lipoic acid, Lipoic acid-PEG-ONH2.
Description:
Lipoic acid PEG Aminooxy (Lipoic acid-PEG-ONH2) is one of Nanocs carbonyl reactive PEG derivatives that have a lipoic acid group on one end of PEG and an aminooxy group (-ONH2) on the other terminus. Lipoic acid, also known as thioctic acid, contains a disufide bond that can bind to gold and other metal surface. It is also an important molecule parting in various biological processes. Aminooxy group (-ONH2), on the other hand, can react with aldehyde or ketone groups derived from polysaccarides or glycoproteins. Reaction between aminooxy and ketone group results in a stable oxime linkage, which is more stable than the schiff base formed between amine and ketone group.
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Nanocs Inc.是全球领先的PEG修饰剂(PEG derivatives, PEGylation试剂)供应商,拥有种类齐全的PEG衍生物,包括:NHS-PEG,马来酰亚胺PEG,巯基PEG,氨基PEG,叠氮PEG,DSPE PEG,荧光PEG等。为全世界数以百万计的客户提供产品与服务。修饰性PEG可应用于药物输送、医疗设备改造和诊断分析等领域。Nanocs提供从磷脂PEGs到荧光PEGs的多种选择,种类齐全,产品线丰富。