DSPE-PEG-COOH, MW 10000
Synonym:1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine PEG Acid, COOH-PEG-DSPE, DSPE-PEG-COOH
Description
DSPE-PEG-COOHis one of Nanocs reactivephospholipid PEGconjugates that can react with primary amine groups. DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is an 18 carbon phospholipid that is highly hydrophobic. PEG linker, on the other hand, offers good hydrophilicity and water solubility. Carboxylic group (-COOH) on the other PEG terminal reacts with primary amine groups using EDC chemistry.PEG DSPEthus can be easily incorporated into liposome and other nanoparticles via the reaction of carboxylic acid and amine.DSPE PEG COOHis a commonly used reactive phospholipid to conjugate antibodies, proteins, peptides or other substrates to the surface of liposome and other lipid PEG nanoparticles. Pegylated phospholipids have longer blood circulation time and higher stability for encapsulated molecules. Nanocs has developed a comprehensive collection of chemical reactive phospholipid PEG products that have high purity, various molecular weights and excellent chemical reactivity. These lipid PEG conjugates demonstrate excellent amphilphilic properties and offer superior advantages for small and large molecule modification, formulation and delivery.
Product Information:
- Form: Solid;
- Color: White;
- Solubility: Soluble in chloroform, warm water;
- Reactive group: Carboxylic acid (-COOH);
- Reactive to: Primary amine group (-NH2);
- Lipid type: C18, saturated;
- Purity: >90%;
Storage Conditions:
- Store at -200C. Avoid frequent thaw and freeze.
Nanocs Inc.是全球领先的PEG修饰剂(PEG derivatives, PEGylation试剂)供应商，拥有种类齐全的PEG衍生物，包括：NHS-PEG，马来酰亚胺PEG，巯基PEG，氨基PEG，叠氮PEG，DSPE PEG，荧光PEG等。为全世界数以百万计的客户提供产品与服务。修饰性PEG可应用于药物输送、医疗设备改造和诊断分析等领域。Nanocs提供从磷脂PEGs到荧光PEGs的多种选择，种类齐全，产品线丰富。
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