Synonym: Maleimide PEG DSPE, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine PEG Maleimide, DSPE-PEG-Mal.
Description:
DSPE PEG Maleimideis one of Nanocs reactivephospholipid PEG reagents that can react with sulfhydryl (thiol, -SH) groups.DSPE (1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine)is a saturated 18C phospholipid that is highly hydrophobic. PEG linker (polyethylene glycol), on the other hand, offers good hydrophilicity and water solubility.MaleimidefunctionalDSPE PEGhas excellent reactivity towards sulfhydryl/thiol groups derived from various molecules. Reaction betweenmaleimideandthiolproceeds easily at neutral pH.Maleimide PEG DSPEis one of most commonly used reactive phospholipids to conjugate antibodies, peptides or other ligands to the surface of liposome and otherlipid PEGnanoparticles. Pegylated phospholipids have longer blood circulation time and higher stability for encapsulated drugs. Nanocs has developed a comprehensive collection of thiol reactivemaleimide phospholipid PEGproducts that have high purity, various molecular weights and excellent chemical reactivity. These lipid PEG conjugates demonstrate excellent amphilphilic properties and offer superior advantages for small and large molecule drug formulation and delivery.
Physical Properties:
- Form: Solid powder;
- Color: White;
- Solubility: Soluble in chloroform and warm water;
- Reactive group: Maleimide;
- Reactive to: Sulfhydryl (-SH);
- Lipid type: 18C PE, saturated;
- Purity: >95%
Storage Conditions:
- Store at -200C. Avoid frequent thaw and freeze.
Nanocs Inc.是全球领先的PEG修饰剂(PEG derivatives, PEGylation试剂)供应商，拥有种类齐全的PEG衍生物，包括：NHS-PEG，马来酰亚胺PEG，巯基PEG，氨基PEG，叠氮PEG，DSPE PEG，荧光PEG等。为全世界数以百万计的客户提供产品与服务。修饰性PEG可应用于药物输送、医疗设备改造和诊断分析等领域。Nanocs提供从磷脂PEGs到荧光PEGs的多种选择，种类齐全，产品线丰富。
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